This report describes a regional approach for improving the nutritional quality of school meals and increasing the selection of healthier foods. Let's Go! is a childhood obesity prevention program that establishes regional workgroups to develop innovative solutions to improve school meal programs. Let's Go! fosters collaborative decision making, specifically addressing the feasibility of proposed strategies, differences in school environments, and level of readiness for change. This approach led to 77 schools achieving the HealthierUS School Challenge and 130 schools implementing Smarter Lunchrooms techniques in school year 2011–2012.